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PHARYNGITIS, AND 

LARYNGITIS


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Anatomy 


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ACUTE PHARYNGITIS


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ACUTE PHARYNGITIS

PATHOLOGY:

Frequently viral

may be secondary to sinonasal disease, caustic 

injury, chronic allergy. Pharyngitis is a common 

condition, particularly in children and young 

adults


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Types of pharyngitis

There are two types of pharyngitis - chronic 

and acute.

Acute pharyngitis is common and is usually 

caused by a viral infection. It's often caused by 

the same viral infection that causes the 

common cold

Chronic pharyngitis is a persistent sore throat


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Acute Pharyngitis

Etiology

Viral >90% 

Rhinovirus – common cold

Coronavirus – common cold

Adenovirus – pharyngoconjunctival fever;acute 

respiratory illness 

Parainfluenza virus – common cold; croup

Coxsackievirus - herpangina

EBV – infectious mononucleosis

HIV


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Acute Pharyngitis

Etiology

Bacterial

Group A beta-hemolytic streptococci (S. pyogenes)*

most common bacterial cause of pharyngitis

accounts for 15-30% of cases in children and 5-10% in 

adults.

Mycoplasma pneumoniae

Arcanobacterium haemolyticum

Neisseria gonorrhea

Chlamydia pneumoniae


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PHARYNGITIS

SIGNS AND 

SYMPTOMS:

sore throat

odynophagia

otalgia (referred)

malaise

fever

erythema 

cervical adenopathy


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PHARYNGITIS

DIAGNOSIS:

clinical exam

consider throat cultures

viral smears rarely indicated


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Suppurative Complications of Group A 

Streptococcal Pharyngitis

Otitis media

Sinusitis

Peritonsillar and retropharyngeal abscesses

Suppurative cervical adenitis


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Streptococcal Cervical Adenitis


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Nonsuppurative Complications of Group A 

Streptococcus

Acute rheumatic fever

follows only streptococcal pharyngitis (not 

group A strep skin infections)

Acute glomerulonephritis

May follow pharyngitis or skin infection 

(pyoderma)


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PHARYNGITIS

supportive care 

bed rest

hydration 

humidity 

lozenges

anesthetic sprays 

(cetacaine or 

xylocaine) iodine 

glyceride solutions

antipyretics

decongestants)

antibiotics for 

suspected bacterial 

infections


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PHARYNGITIS

Other causes: 

Candidiasis

Infectious Mononucleosis

Herpangina

Diphtheria

Scarlet Fever


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CHRONIC PHAYNGITIS


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CHRONIC PHARYNGITIS

ETIOLOGIES

granulomatous

diseases

connective tissue 

disorders

malignancies

postnasal drip 

(chronic 

rhinosinusitis) 

Irritants 

dust, 

dry heat, 

chemicals,

smoking,

alcohol


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CHRONIC PHARYNGITIS

Signs and Symptoms

constant throat 

clearing

dry throat

odynophagia

thickened and granular 

pharyngeal wall

pharyngeal crusting


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The typical appearance of a granulating 

inflammation involving the posterior wall 

of the pharynx (hypertrophic form).

CHRONIC PHARYNGITIS


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CHRONIC PHARYNGITIS

clinical history and examination

culture and biopsy if failed empiric therapies


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CHRONIC PHARYNGITIS

Treatment

address underlying etiology

avoidance of contributing factors 

smoking

dust

dry environments

symptomatic treatment similar to acute 

pharyngitis


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LARYNGITIS


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Anatomy


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DEFINITION

It is the acute inflammation of larynx leading 

to oedema of laryngeal mucosa and 

underlying structures.


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PAEDIATRIC CONCERNS

Lacks firm cartilaginous skeleton.

Flabby , easily collapses.

Glottic aperture , relatively smaller.

Mucosa  swells up rapidly in response to 

slightest trauma or infection.

Stridor is the most noticeable presentation.


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AETIOLOGY

INFECTIOUS:

Viral

Bacterial 

NON INFECTIOUS

Inhaled fumes

Allergy

Polluted atmospheric conditions

Vocal abuse

Iatrogenic trauma                       


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CLINICAL PRESENTATION

Hoarseness or change in voice.

Husky, high pitched voice.

Discomfort in throat, pain.

Body aches. 

Dysphagia, Dyspnoea.

Dry irritating paroxysmal cough.

Fever, Malaise.


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CLINICAL DIAGNOSIS

Signs of acute URTI.

Dry thick sticky 

secretions.

Dusky red and swallon 

vocal cords.

Diffuse congestion of 

laryngeal mucosa.


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DIFFERENTIAL DIAGNOSIS

Acute epiglottitis

Acute laryngo tracheo bronchitis.

Laryngeal perichondritis

Laryngeal oedema

Laryngeal diphtheria

Reinke’s oedema


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TREATMENT

SUPPORTIVE

Voice rest.

Steam inhalation.

Cough suppressants.

Avoid smoking and cold.

Fluid intake.


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TREATMENT  Cont

DEFINITIVE

ANTIBIOTICS

STEROIDS

ANALGESICS


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Chronic Laryngitis

Presents as diffuse lesion or produce localized 

effects in larynx

Chronic infections in the surrounding areas,vocal

abuse smoking, alcohal,irritant fumes are held 

aetiological factors.

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Chronic laryngitis has a 

multifactorial etiology and is ofen 

exacerbated by intercurrent viral 

and bacterial infections 

CAUSES OF CHRONIC LARYNGITIS


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chronic laryngitis differential

Reinkes oedema

vocal nodules

vocal cord polyp

Contact ulcer

Hyperkeratosis and leukoplakia

Atrophic laryngitis

Laryngeal lupus

tuberculous laryngitis


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Tuberculous laryngitis

Almost always to secondary to pulmonary TB

Infected sputum

Younger age group

Tubercle formation is characteristic

Infilteration stage followed by proliferative 

stage

Posterior part of larynx involved


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Reflux-Induced Laryngitis

inflammatory response of laryngeal mucosa 

from Laryngopharyngeal Acid Reflux (LPR)


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Reflux induced Laryngitis

Laryngeal Findings:

Erythema and edema 

of

Posterior commissure

Arytenoids

Superior surface of 

the vocal fold

Laryngeal surface of 

the epiglottis


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CHRONIC LARYNGITIS

Treatment:

Address etiology 

stop smoking

voice rehabilitation

Treatrhinosinusitis

reflux regimen

Humidification

Mucolytics

Consider short course 

of corticosteroids


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Term applied to group of inflammatory

conditions involving larynx , trachea and
characterized by Triad :

Inspiratory stridor

Brassy cough

Hoarseness of voice +/_ resp.distress


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Usually  viral in origin 

-

Parainfluenza virus (type 1)

- Influenza virus 
- RSV , adenovirus , measles virus

It is the 

most common

cause of Acute Airway 

Obstruction in children

Age group 3m-3 years (peak 2years)

Affects boys more often than girls

Peak occurrence is in  fall and winter


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It is clinically diagnosed 

Neck x-ray  and CBC  all should be done 

in clinically stable pt .

- AP neck film : show a pencil tip or 

steeple sign of the subglottic trachea 

- CBC , it may helps . 


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 It is a rapidly progreesive bacterial infection

causing acute inflammation and edema of the
epiglottis and adjacent structures : aryepiglottic
folds and arytenoids

 Also known as supraglottitis

 It is life threatening condition may lead to

sudden and complete airway obstruction


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Age : 2-6 years ( peak at 3 year)

Infant , older children  and adult are 

rarely affected

Causative agents : 

-

HIB

- pneumococci , staphylococci,    

streptococci 


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History
Presentation
Appearance of the child

Pharynx examination at this stage in ER 
is absolutely contraindicated

Next step = admission in ICU

Neck x-ray : Not the priority

Do not leave the patient unattended


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THANK YOU!!!




رفعت المحاضرة من قبل: Bakr Zaki
المشاهدات: لقد قام عضوان و 77 زائراً بقراءة هذه المحاضرة








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