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Signs in Thoracic Imaging

Carlos H. Previgliano MD

Associate Professor Radiology

Director of Cardiothoracic Radiology

Louisiana State University

– Shreveport 


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Objectives

• Recognize some important radiologic 

signs in thoracic imaging

• Understand the mechanism of these 

thoracic radiologic signs

• Establish diagnosis of particular thoracic 

diseases using these signs


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Radiologic Signs

• Radiologic signs are recognizable and 

characteristic patterns

• Used to describe abnormalities

• Visualized on imaging methods

• Aid in the diagnosis and subsequent 

treatment of different diseases


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Air Bronchogram Sign

• Occurs in infiltration or edema in tissues 

adjacent to patent bronchi

• Visualized on chest radiographs or CT
• Associated with airspace disease 
• Absence in obstructive atelectasis  
• Darker tubular densities are seen 


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• The sign implies:

• patency of proximal airways
• evacuation of alveolar air by 

absorption (atelectasis), replacement 
(pneumonia) or combination of both 

• Consolidation, tumor, lymphoma

Air Bronchogram Sign


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Air Crescent Sign

• Can be visualized in X-rays and CT
• Crescentic collection of air within 

consolidation or nodular opacity

• Seen in pulmonary cavitary process
• Usually announces recovery
• It is a result of increased granulocyte 

activity


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• Characteristic of invasive pulmonary 

aspergillosis

• Tumor, hematoma, Wegener 

granulomatosis, hydatid cyst, TB, 
nocardiosis, bacterial abscess

• Not confused with Monod’s sign

• air surrounding fungus ball or mycetoma in 

preexisting cavity 

Air Crescent Sign


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Continuous Diaphragm Sign

• Described by Levin in 1973
• Normally central part of diaphragm is 

lost due to apposition of heart

• Air interposed between the heart and 

diaphragm results in gas-tissue interface

• Seen on chest radiographs
• Characteristic of pneumomediastinum


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Deep Sulcus Sign

• Seen on radiographs in supine position
• Characteristic of pneumothorax
• 30% pneumothoraces are undetected
• Lucency in lateral costophrenic angle  
• Air collects anteriorly and basally 
• Useful in neonates and ill patients
• Include lateral costophrenic angles


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Ring Around Artery Sign

• Visualized on lateral chest radiographs
• Lucency along or surrounding RPA
• Characteristic of pneumomediastinum
• Usually is accompanied by other 

ancillary signs:

• continuous diaphragm sign
• Naclerio’s V sign
• thymic sail sign


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Thymic Sail Sign

Naclerio’s V Sign


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Flat Waist Sign

• Described by Kattan and Wlot in 1976
• Indicates left lower lobe collapse
• Visualized on frontal views
• Perfectly symmetrical PA or AP view
• Hilar structures shift downward and 

rotation of heart produces flattening of 
cardiac waist 


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Finger-in-Glove Sign

• Visible on chest radiographs or CT
• Indicates mucoid impaction within an 

obstructed bronchus 

• Characterized by branching tubular or 

fingerlike opacities


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• Originate from the hilum and are 

directed peripherally 

• Also seen in cases of dilated bronchi 

with secretions  

• Distal lung remains aerated by collateral 

drift through interalveolar pores (pores 
of Kohn) and Lambert canal

Finger-in-Glove Sign


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Golden S Sign

• Can be seen on PA/Lateral views & CT
• Described by Ross Golden in 1925
• Typically seen with RUL collapse, can 

also be seen w collapse of other lobes

• Resembles a reverse S shape also 

referred as reverse S sign of Golden


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• Medial portion of minor fissure is convex 

inferiorly due to a central mass

• Lateral portion of the fissure is concave 

inferiorly

Golden S Sign


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• Should raise suspicion of central 

neoplasm:

• bronchial carcinoma
• primary mediastinal tumor
• metastasis
• enlarged lymph nodes 

Golden S Sign


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Luftsichel Sign

• German for sickle of air (luft: air sichel: 

crescent)

• Paramediastinal lucency due to 

interposition of lower lobe apex between 
mediastinum and shrunken upper lobe

• Occurs more commonly on the left than 

in the right


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Double Density Sign

• Indicates left atrial enlargement
• Occurs when right side of the left atrium 

pushes into adjacent lung

• Splaying of the carina
• Superior displacement of left main stem 

bronchus on frontal view


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• Posterior displacement of left main stem 

bronchus on lateral view

• Posterior displacement of esophagus on 

barium study

Double Density Sign


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Walking Man Sign


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Doughnut Sign

• Detect mediastinal adenomegaly
• Lateral chest radiograph
• Subcarinal lymphadenopathy
• Mass posterior to bronchus intermedius 

and inferior hilar window

• CT primary modality for detecting 

mediastinal lymphadenopathy


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Normal

Lymphadenopathy

Pulmonary hypertension


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Silhouette Sign

• If an intra-thoracic radio-opacity is in 

anatomic contact with a border of heart 
or aorta will obscure that border

• An intra-thoracic lesion not anatomically 

contiguous with a border or a normal 
structure will not obliterate that border

• Definition given by B. Felson in 1950


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Silhouette Sign

• Reliable sign distinguishing anterior lung 

lesions from posterior or lower lesions

• When two objects same density touch 

each other the edge between them 
disappears 


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Silhouette Sign

Silhouette/structure

• Upper R heart/asc. Ao
• Right heart border
• Upper left heart border
• Left heart border
• Aortic knob
• Hemidiaphragm

Contact with lung

• Ant segment RUL
• RML (medial)
• Ant segment LUL
• Lingula (anterior)
• Apical portion LUL
• Lower lobes 


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Cervicothoracic Sign

• Used to determine location of 

mediastinal lesion in the upper chest

• Based on  principle that an intrathoracic 

lesion in direct contact with soft tissues 
of the neck will not outlined by air

• Uppermost border of the anterior 

mediastinum ends at level of clavicles


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• Middle and posterior mediastinum 

extends above the clavicles

• Mediastinal mass projected superior the 

level of clavicles must be located either 
within middle or posterior mediastinum

• More cephalad the mass extends the 

most posterior the location

Cervicothoracic Sign


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T1+C

T1+C


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Thoracoabdominal Sign

• Posterior costophrenic sulcus extends 

more caudally than anterior basilar lung 

• Lesion extends below the dome of 

diaphragm must be in posterior chest 
whereas lesion terminates at dome must 
be anterior 

• Cervicothoracic and thoracoabdominal 

signs were described by Felson


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Tapered Margins Sign

• A lesion in the chest wall, pleura or 

mediastinum have smooth tapered 
borders and obtuse angles

• While parenchymal lesions usually form 

acute angles


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1-2-3 Sign

• Characterized by bilateral hilar and right 

paratracheal lymphadenopathy 

• so-called Garland triad or 1-2-3 sign

• Suggestive of sarcoidosis
• Separation between nodes and heart 

which is not seen in lymphoma


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1

2

3


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Epicardial Fat Pad Sign

• Indicates pericardial effusion 
• Kremens and Torrance in 1955 were the 

first to draw attention in this sign 

• Epicardial fat allows the silhouette of two 

layers pericardium to appear separate 
from the heart

• Normally pericardium measures 1-2 mm 


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• Thickness exceeding 2 mm suggests 

pericardial effusion

• Widening of pericardial shadow creates 

appearance of inward displacement of 
epicardial fat

• Rarely is due to extrapericardial disease

Epicardial Fat Pad Sign


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Pericardial Effusion

Imaging Findings

• Conventional radiography

• water bottle configuration
• loss of retrosternal clear space
• epicardial fat pad sign  

• Echocardiogram study of choice
• CT may detect small effusions (50 cc)
• MRI characterize fluid


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Water Bottle Sign


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Hampton’s Hump Sign

• Described by Audrey Hampton in 1940
• Peripheral wedge-shaped opacity due to 

infarction

• Pleura-based consolidation in the form 

of truncated cone w base against pleural 
surface and apex pointing toward hilum


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Westermark Sign

• Described by Neils Westermark in 1938
• Chest radiograph and CT show 

increased lucency or hypoattenuation

• Typically signifies either occlusion of a 

larger lobar/segmental artery or 
widespread small vessel occlusion 


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Westermark Sign

• Represents oligemia distal to PE
• Seen only in 2% of patients
• Sign results from combination of

• dilatation pulmonary arteries proximal embolus
• collapse of distal vasculature  

• Low sensitivity 11%, high specificity 92%


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Fleischner Sign 

• Described by Felix Fleischner 
• Enlargement proximal pulmonary 

arteries on plain film or angiography

• PA enlargement due to embolus
• Commonly in the setting of massive PE
• It has relatively low sensitivity
• Abrupt tapering of an occluded vessel 

distally (knuckle sign)


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Hilum Overlay Sign

• Described by B. Felson
• If hilar vessels are sharply delineated it 

can be assumed that the overlying mass 
is anterior or posterior 

• If mass inseparable pulmonary arteries 

structures are adjacent to one another


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Hilum Convergence Sign

• Described by B. Felson 
• Used to distinguish between a prominent 

hilum and an enlarged pulmonary artery

• If branches of PA converge toward 

central mass is an enlarged PA

• If branches of PA converge toward heart 

rather than mass is a mediastinal tumor


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Fallen Lung Sign

• Partial or complete tear of tracheal/mainstem 

or lobar bronchi is a result of penetrating or 
blunt trauma (high speed road accident)

• 1.5% of cases of blunt chest trauma
• 80% tracheo-bronchial ruptures within 2.5 cm 

of carina 

• Fallen lung sign is highly specific but 

uncommon finding


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Fallen Lung Sign

• Two mechanisms in blunt trauma:

- reflex closure glottis causes rise pressure

- shearing forces produced deceleration and

rotation

• Airway injury may be obscured by other 

injuries

• Many cases remain undiagnosed until 

complications develop


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CT Angiogram Sign

• Finding may be seen on CT of chest 

after IV contrast material administration

• Consists of enhancing branching 

pulmonary vessels in homogeneous low-
attenuating consolidation

• Low-attenuating component can be 

caused by production of mucin within air 
spaces


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• Initially described by Im in 1990 as a 

specific sign (92%) of lobar BAC

• Also seen in:

• pneumonia
• pulmonary edema
• obstructive pneumonitis central tumor
• metastasis from GI carcinomas
• lymphoma

CT Angiogram Sign


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CT Halo Sign

• Ground glass attenuation surrounding a 

pulmonary nodule/mass on CT images

• Described by Kuhlman in 1985 in 

patients with invasive aspergillosis 

• Associated w hemorrhagic nodules and 

may be caused neo or inflammatory 

• Disease pathologically active with tumor 

spread, hemorrhage or inflammation 


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CT halo sign: Diseases

Lee YR et al. British Journal of Radiology 2005;78:862-865


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Halo Sign

• Should be familiar with adequate clinical 

setting help to narrow differentials

• multiple nodules immunocompromised 

patients could be infections, Kaposi or 
lymphoma

• leukemia or BMT and fever may represent 

invasive aspergillosis

• immunocompetent patients with a solitary 

nodule may indicate BAC 


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Reverse Halo Sign

• Central ground-glass opacity surrounded 

by denser consolidation of crescentic or 
ring shape, at least 2 mm thick

• First described by Voloudaki in 1996
• Kim in 2003 used the term reverse halo
• Found to be relatively specific for crypto-

genic organizing pneumonia (COP)


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Reverse Halo Sign

• Seen in other conditions:

• Wegener’s granulomatosis
• lymphomatoid granulomatosis
• paracoccidiodomycosis
• neoplastic (metastasis)
• invasive aspergillosis
• lipoid pneumonia


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Split Pleura Sign

• Seen on contrast enhanced CT of chest
• Thickened visceral and parietal pleura 

with separation by a collection

• Empyema or exudative effusion
• Exudative: bacterial pneumonia, cancer, 

viral infection, PE


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Tree-in-Bud Sign

• Commonly seen at thin-section CT
• Initially described in endobronchial 

spread of Tuberculosis

• Recognized in diverse entities
• Small centrilobular nodules  soft-tissue 

attenuation connected to multiple 
branching structures


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Rossi SE et al. RadioGraphics 2005;25:789-801

Tree-in-Bud 

– Causes  


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Crazy Paving Sign

• Scattered or diffuse GG attenuation w 

superimposed intralobular and 
interlobular septa thickening

• Commonly seen at thin-section CT
• Initially described in PAP
• Recognized in diverse entities


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Crazy-Paving 

– Causes 

Rossi SE et al. RadioGraphics 2003;23:1509-1519


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Comet Tail Sign

• Seen on CT of the chest
• Consists of curvilinear opacity extending 

from subpleural mass toward hilum

• Produced by the distortion vessels and 

bronchi that lead to adjacent rounded 
atelectasis


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Comet Tail Sign

• Rounded atelectasis is not rare, 

described in patients with asbestosis 

• Other conditions: CHF, Dressler, infarct, 

TB or parapneumonic effusions, 
histoplasmosis

• Round or oval opacity 2.5-8 cm, acute 

angles, lower lobes, enhancement

• DD includes bronchogenic Ca


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Signet Ring Sign

• Seen on CT/HRCT scans of chest
• CT finding in patient with bronchiectasis
• Ring shadow representing dilated thick-

walled bronchus associated a nodular 
opacity representing pulmonary artery

• Distinguish from cystic lung lesions


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Pearl ring sign


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Thank you!!




رفعت المحاضرة من قبل: Abdalmalik Abdullateef
المشاهدات: لقد قام 40 عضواً و 355 زائراً بقراءة هذه المحاضرة








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